EMD-68389

Single-particle
2.2 Å
EMD-68389
3D View Gallery
Deposition: 14/01/2026
Map released: 04/02/2026
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-68389
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 22jy summary report (pdf.gz) Map and 22jy FULL report (pdf.gz)
EMICSS annotations (xml)

P301L/S320F human tau filaments from mouse brain

EMD-68389

Single-particle
2.2 Å
EMD-68389
3D View Gallery
Deposition: 14/01/2026
Map released: 04/02/2026
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: P301L/S320F human tau filaments
Fitted models: 22jy

Deposition Authors: Yanagisawa H, Kano M, Kimura T, Kikkawa M, Tomita T
Cryo-EM structure of pro-aggregant P301L/S320F double-mutant tau filaments formed in mouse brains following peripheral AAV delivery
Kano M, Kimura T, Yanagisawa H, Tatsumi L, Yamashita K, Sakai A, Li X, Saido TC, Saito T, Takatori S, Kikkawa M, Tomita T
(2026) bioRxiv
DOI: doi:10.64898/2026.01.19.700132
ISSN: 2692-8205