EMD-67804

Single-particle
3.11 Å
EMD-67804
3D View Gallery
Deposition: 17/12/2025
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-67804

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-21lt summary report (pdf.gz) Map-21lt FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of the setmelanotide-bound human melanocortin receptor 4 (MC4R)-Gq complex

EMD-67804

Single-particle
3.11 Å
EMD-67804
3D View Gallery
Deposition: 17/12/2025
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Homo sapiens, Bos taurus
Sample: Cryo-EM structure of setmelanotide-bound human melanocortin receptor 4 in complex with Gq protein
Fitted models: 21lt

Deposition Authors: Feng WB, Zhou QT, Wang MW
Rationale of renewed efforts in developing MC4R modulators to treat metabolic disorders
Feng W, Zhou Q, Wang MW
(2026) Acta Pharm Sin B
DOI: doi:10.1016/j.apsb.2026.06.035
ISSN: 2211-3843