EMD-67801

Single-particle
3.11 Å
EMD-67801
3D View Gallery
Deposition: 17/12/2025
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-67801

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Setmelanotide bound to MC4R-Gq complex.Consensus refinement

EMD-67801

Single-particle
3.11 Å
EMD-67801
3D View Gallery
Deposition: 17/12/2025
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of setmelanotide-bound human melanocortin receptor 4 in complex with Gq protein

Deposition Authors: Feng WB
Rationale of renewed efforts in developing MC4R modulators to treat metabolic disorders
Feng W, Zhou Q, Wang MW
(2026) Acta Pharm Sin B
DOI: doi:10.1016/j.apsb.2026.06.035
ISSN: 2211-3843