EMD-67431

Single-particle
2.7 Å
EMD-67431
3D View Gallery
Deposition: 03/12/2025
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-67431

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-20zi summary report (pdf.gz) Map-20zi FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the human neurotensin receptor 1 (hNTSR1)-Gi1 complex in the GTP-bound, AHD-open NC state 1, plunge-frozen 0-5 seconds after GTP addition

EMD-67431

Single-particle
2.7 Å
EMD-67431
3D View Gallery
Deposition: 03/12/2025
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus, synthetic construct
Sample: JMV449-bound human neurotensin receptor 1 (hNTSR1)-Gi1 complex in the GTP-bound, AHD-open NC state 1 with scFv16, plunge-frozen 0-5 seconds after GTP addition
Fitted models: 20zi

Deposition Authors: Kobayashi K , Matsui TE, Fukuda M , Kawakami K , Yamashita K , Kato HE , Kato HE
The dynamic basis of G-protein recognition and activation by a GPCR.
Kobayashi K , Kawakami K , Matsui TE, Yokoi S, Fukuda M , Narita TJ, Arai H, Tambo M, Sumikama T , Tatsumi M, Yamashita K , Koyanagi J, Kugawa M, Ikeda H, Sumino A, Mitsutake A , Kobilka BK , Inoue A , Kato HE
(2026) Nature , 652 , 812 - 821
PUBMED: 41813902
DOI: doi:10.1038/s41586-026-10228-w
ISSN: 1476-4687
ASTM: NATUAS