EMD-67427

Single-particle
2.8 Å
EMD-67427
3D View Gallery
Deposition: 03/12/2025
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-67427
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 20zd summary report (pdf.gz) Map and 20zd FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human Neurotensin Receptor 1 (hNTSR1)-Gi1 (delipidated) complex in nucleotide-free NC state

EMD-67427

Single-particle
2.8 Å
EMD-67427
3D View Gallery
Deposition: 03/12/2025
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: JMV449-bound human Neurotensin Receptor 1 (hNTSR1)-Gi1 (delipidated) complex in nucleotide-free NC state with scFv16
Fitted models: 20zd

Deposition Authors: Kobayashi K, Matsui TE, Fukuda M, Kawakami K, Yamashita K, Kato HE, Kato HE
The dynamic basis of G-protein recognition and activation by a GPCR.
Kobayashi K, Kawakami K, Matsui TE, Yokoi S, Fukuda M, Narita TJ, Arai H, Tambo M, Sumikama T, Tatsumi M, Yamashita K, Koyanagi J, Kugawa M, Ikeda H, Sumino A, Mitsutake A, Kobilka BK, Inoue A, Kato HE
(2026) Nature , 652 , 812 - 821
PUBMED: 41813902
DOI: doi:10.1038/s41586-026-10228-w
ISSN: 1476-4687
ASTM: NATUAS