EMD-66845

Helical reconstruction
2.63 Å
EMD-66845
3D View Gallery
Deposition: 30/10/2025
Map released: 04/11/2026
Last modified: 04/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-66845

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9xgf summary report (pdf.gz) Map-9xgf FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Type B 2N4R human tau filaments induced by heparan sulfate with a single-protofilament fold

EMD-66845

Helical reconstruction
2.63 Å
EMD-66845
3D View Gallery
Deposition: 30/10/2025
Map released: 04/11/2026
Last modified: 04/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Tau
Fitted models: 9xgf

Deposition Authors: Zeng W , Sun S , Shi Y , He Z

Golgi-derived glycosaminoglycans are involved in pathological tau seeds formation as the cofactor in Alzheimer's disease and related tauopathies
Zeng W , Sun S , Li Q, Sun Z, Hu Y, Duan J, Zhao B, Zheng H, EunRan S, Vivianna MVD, Xu P, Yu B, Qiu H, Yuan W, Shi Y , He Z
To Be Published