EMD-66770
Cryo-EM structure of H3K122ac nucleosome
EMD-66770
Single-particle3.07 Å
Deposition: 27/10/2025Map released: 04/11/2026
Last modified: 04/11/2026
Sample Organism:
Homo sapiens,
synthetic construct
Sample: The H3K122ac nucleosome with scFv
Fitted models: 9xdp
Deposition Authors: Oishi T
,
Hatazawa S ,
Kujirai T ,
Kato J,
Kobayashi Y ,
Ogasawara M ,
Takizawa Y ,
Kurumizaka H
Sample: The H3K122ac nucleosome with scFv
Fitted models: 9xdp
Deposition Authors: Oishi T
,
Hatazawa S ,
Kujirai T ,
Kato J,
Kobayashi Y ,
Ogasawara M ,
Takizawa Y ,
Kurumizaka H
Structural basis for site-specific histone H3 acetylation-dependent regulation of RNAPII transcription through nucleosomes
Oishi T ,
Hatazawa S ,
Kujirai T ,
Suzuki S,
Nakatsu K ,
Hayashi G ,
Kato J,
Kobayashi Y ,
Ogasawara M ,
Ehara H ,
Sekine S,
Takizawa Y ,
Kurumizaka H
To Be Published
,
Hatazawa S ,
Kujirai T ,
Suzuki S,
Nakatsu K ,
Hayashi G ,
Kato J,
Kobayashi Y ,
Ogasawara M ,
Ehara H ,
Sekine S,
Takizawa Y ,
Kurumizaka H
To Be Published
Grant Support:
- Japan Society for the Promotion of Science (JSPS): JP25K24594 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP24H02319 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP24H02328 (Japan)
- Japan Science and Technology: JPMJER1901 (Japan)
- Japan Science and Technology: JPMJCR24T3 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP25ama121009 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP25KJ1033 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP25K18410 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP23K17392 (Japan)
- Japan Science and Technology: JPMJSP2108 (Japan)
- Japan Science and Technology: JPMJPR25N9 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP25ama121002 (Japan)