EMD-66115

Single-particle
2.54 Å
EMD-66115
3D View Gallery
Deposition: 04/09/2025
Map released: 14/10/2026
Last modified: 14/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-66115

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9wne summary report (pdf.gz) Map-9wne FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the LbCas12a-Lid2-crRNA-DNA complex

EMD-66115

Single-particle
2.54 Å
EMD-66115
3D View Gallery
Deposition: 04/09/2025
Map released: 14/10/2026
Last modified: 14/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Lachnospiraceae bacterium ND2006
Sample: LbCas12a-Lid2.3-crRNA-target DNA
Fitted models: 9wne

Deposition Authors: Omura SN, Warren Villegas R, Van der Oost J, Nureki O, Warren VR, Hirano H, Kusakizako T, Kise Y, Lebbink HGJ, Itoh Y

Engineering and characterization of a novel Cas12a nickase
Warren Villegas R, Omura SN, Castro DR, Sudfeld C, Luteijn M, Morinaga H, Inoue WJ, Shuto Y, Vleesschauwer DD, Staals RHJ, Nureki O, Wu WY, Van der Oost J
To Be Published