EMD-66049

Helical reconstruction
3.09 Å
EMD-66049
3D View Gallery
Deposition: 02/09/2025
Map released: 03/06/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-66049

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9wl8 summary report (pdf.gz) Map-9wl8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

ALECT2 type IIb filament from renal biopsy tissue of an individual with ALECT2 amyloidosis

EMD-66049

Helical reconstruction
3.09 Å
EMD-66049
3D View Gallery
Deposition: 02/09/2025
Map released: 03/06/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Leukocyte chemotactic factor 2 amyloid filaments
Fitted models: 9wl8

Deposition Authors: Zheng J, Zheng Y , Shi Y
Cryo-EM structures of ALECT2 filaments from human renal biopsies.
Zheng JL , Zheng YX, Chen K, Wang S, Liang JW, Wang SX , Yang L , Shi Y
(2026) Nat Commun , 17
PUBMED: 42173881
DOI: doi:10.1038/s41467-026-73602-2
ISSN: 2041-1723