EMD-65890
Structure of mC5aR2 in complex with mC5a-desArg
EMD-65890
Single-particle3.33 Å
Deposition: 19/08/2025Map released: 01/07/2026
Last modified: 15/07/2026
Sample Organism:
Mus musculus
Sample: mC5aR2 bound to mC5a-desArg
Fitted models: 9wdi
Deposition Authors: Tiwari D, Sano FK, Yadav MK, Sawada K, Ganguly M, Mishra S, Dalal A
,
Banerjee R,
Nureki O,
Shukla AK
Sample: mC5aR2 bound to mC5a-desArg
Fitted models: 9wdi
Deposition Authors: Tiwari D, Sano FK, Yadav MK, Sawada K, Ganguly M, Mishra S, Dalal A
,
Banerjee R,
Nureki O,
Shukla AK
Molecular mechanisms of naturally encoded signaling bias at the complement anaphylatoxin receptors.
Tiwari D,
Sawada K,
Dalal A ,
Mishra S,
Li XX ,
Dent JC,
Kim K,
Yadav MK,
Roy N,
Ganguly M,
Banerjee N,
Stepniewski TM,
Ahn D ,
Yamaguchi K,
Oshima HS,
Hashimoto K,
Fung JN,
Lerskiatiphanich T ,
Cui CS ,
Lee JD,
Selent J,
Inoue A,
Clark RJ,
Chung KY,
Banerjee R,
Sano FK,
Woodruff TM,
Nureki O,
Shukla AK
(2026) Mol Cell , 86 , 2586
,
Mishra S,
Li XX ,
Dent JC,
Kim K,
Yadav MK,
Roy N,
Ganguly M,
Banerjee N,
Stepniewski TM,
Ahn D ,
Yamaguchi K,
Oshima HS,
Hashimoto K,
Fung JN,
Lerskiatiphanich T ,
Cui CS ,
Lee JD,
Selent J,
Inoue A,
Clark RJ,
Chung KY,
Banerjee R,
Sano FK,
Woodruff TM,
Nureki O,
Shukla AK
(2026) Mol Cell , 86 , 2586
Grant Support:
- Wellcome Trust: IA/S/20/1/504916 (United Kingdom)
- Science and Engineering Research Board (SERB): IPA/2020/000405 (India)
- Science and Engineering Research Board (SERB): CRG/2022/002646 (India)