EMD-65737

Single-particle
2.81 Å
EMD-65737
3D View Gallery
Deposition: 07/08/2025
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65737

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9w81 summary report (pdf.gz) Map-9w81 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human pyruvate kinase R (PKR) in complex with an allosteric activator FT-4202

EMD-65737

Single-particle
2.81 Å
EMD-65737
3D View Gallery
Deposition: 07/08/2025
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: PKR tetramer in complex with allosteric activator FT-4202
Fitted models: 9w81

Deposition Authors: Ma HY, Su ZM

Structural insights into allosteric activation of pyruvate kinase R by mitapivat and novel agonists
Ma HY, Su ZM
To Be Published