EMD-65663

Single-particle
2.63 Å
EMD-65663
3D View Gallery
Deposition: 01/08/2025
Map released: 22/04/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65663

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9w5i summary report (pdf.gz) Map-9w5i FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

AGO maturation complex (AMC): AGO2-miRNA duplex in complex with Hsp90 beta and co-chaperone p23

EMD-65663

Single-particle
2.63 Å
EMD-65663
3D View Gallery
Deposition: 01/08/2025
Map released: 22/04/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of AGO2 with miRNA and Hsp90-p23
Fitted models: 9w5i

Deposition Authors: Lee H, Jeong M-S, Lee Y-Y, Lee J-H, Lee D, Kim VN, Roh S-H
Structural basis for chaperone-guided assembly of RNA-induced silencing complex.
Lee YY, Jeong M, Lee H, Lee D, Lee J, Park J, Kim VN, Roh SH
(2026) Nature , 655 , 1339 - 1348
PUBMED: 42271054
DOI: doi:10.1038/s41586-026-10640-2
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: