EMD-65661

Single-particle
2.63 Å
EMD-65661
3D View Gallery
Deposition: 01/08/2025
Map released: 22/04/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65661

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Focused map of AGO2 MID/PIWI domain from Hsp90-p23-AGO2-miRNA duplex

EMD-65661

Single-particle
2.63 Å
EMD-65661
3D View Gallery
Deposition: 01/08/2025
Map released: 22/04/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of AGO2 with miRNA and Hsp90-p23

Deposition Authors: Lee H , Jeong M-S, Lee Y-Y, Lee J-H, Lee D, Kim VN, Roh S-H
Structural basis for chaperone-guided assembly of RNA-induced silencing complex.
Lee YY, Jeong M, Lee H , Lee D, Lee J, Park J, Kim VN, Roh SH
(2026) Nature , 655 , 1339 - 1348
PUBMED: 42271054
DOI: doi:10.1038/s41586-026-10640-2
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: