Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-65622
Cryo-EM structure of human kappa opioid receptor -G protein signaling complex bound with U-50488H
EMD-65622
Single-particle2.9 Å
Deposition: 31/07/2025Map released: 19/11/2025
Last modified: 19/11/2025
Sample Organism:
Homo sapiens,
Mus musculus
Sample: Kappa-type opioid receptor-Gi protein-bound U-50488
Fitted models: 9w49
Deposition Authors: Suno-Ikeda C, Takai T, Hirose M, Inoue A
,
Sugita Y ,
Kato T ,
Kobayashi T ,
Suno R
Sample: Kappa-type opioid receptor-Gi protein-bound U-50488
Fitted models: 9w49
Deposition Authors: Suno-Ikeda C, Takai T, Hirose M, Inoue A
,
Sugita Y ,
Kato T ,
Kobayashi T ,
Suno R
Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor.
Suno-Ikeda C,
Nishikawa R,
Suzuki R ,
Yokoi S ,
Iwata S,
Takai T,
Ogura T,
Hirose M,
Tokuda A,
Katamoto R,
Inoue A ,
Asai E,
Kise R ,
Sugita Y ,
Kato T ,
Nagase H ,
Mitsutake A ,
Saitoh T ,
Katayama K ,
Inoue A ,
Kandori H ,
Kobayashi T ,
Suno R
(2025) Nat Commun , 16 , 9392 - 9392
,
Yokoi S ,
Iwata S,
Takai T,
Ogura T,
Hirose M,
Tokuda A,
Katamoto R,
Inoue A ,
Asai E,
Kise R ,
Sugita Y ,
Kato T ,
Nagase H ,
Mitsutake A ,
Saitoh T ,
Katayama K ,
Inoue A ,
Kandori H ,
Kobayashi T ,
Suno R
(2025) Nat Commun , 16 , 9392 - 9392
Grant Support: