EMD-65622

Single-particle
2.9 Å
EMD-65622
3D View Gallery
Deposition: 31/07/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65622

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9w49 summary report (pdf.gz) Map-9w49 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human kappa opioid receptor -G protein signaling complex bound with U-50488H

EMD-65622

Single-particle
2.9 Å
EMD-65622
3D View Gallery
Deposition: 31/07/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Kappa-type opioid receptor-Gi protein-bound U-50488
Fitted models: 9w49

Deposition Authors: Suno-Ikeda C, Takai T, Hirose M, Inoue A , Sugita Y , Kato T , Kobayashi T , Suno R
Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor.
Suno-Ikeda C, Nishikawa R, Suzuki R , Yokoi S , Iwata S, Takai T, Ogura T, Hirose M, Tokuda A, Katamoto R, Inoue A , Asai E, Kise R , Sugita Y , Kato T , Nagase H , Mitsutake A , Saitoh T , Katayama K , Inoue A , Kandori H , Kobayashi T , Suno R
(2025) Nat Commun , 16 , 9392 - 9392
PUBMED: 41152269
DOI: doi:10.1038/s41467-025-64882-1
ISSN: 2041-1723