EMD-65437

Single-particle
2.48 Å
EMD-65437
3D View Gallery
Deposition: 19/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65437
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9vxp summary report (pdf.gz) Map and 9vxp FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human Pyruvate kinase R (PK-R)

EMD-65437

Single-particle
2.48 Å
EMD-65437
3D View Gallery
Deposition: 19/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human pyruvate kinase R homotetramer
Fitted models: 9vxp

Deposition Authors: Ma HY, Su ZM

Structural insights into allosteric activation of pyruvate kinase R by mitapivat and novel agonists
Ma HY, Su ZM
To Be Published