EMD-65304

Single-particle
2.74 Å
EMD-65304
3D View Gallery
Deposition: 09/07/2025
Map released: 17/09/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65304

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9vsq summary report (pdf.gz) Map-9vsq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The TUG-891-bound structure of TMEM175

EMD-65304

Single-particle
2.74 Å
EMD-65304
3D View Gallery
Deposition: 09/07/2025
Map released: 17/09/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: DCY1020-bound structure of TMEM175
Fitted models: 9vsq

Deposition Authors: Zhu X, Liu H, Yin W
Structural insights into the activation of TMEM175 by small molecule.
Zhu X, Ping M, Liu H, Yu T, Jiang Z, Liu Z, Li C, Hou X, Chu Q, Li S, Mao C, Luo T, Kang C, Wang F, Yang C, Tang M, Jiang Z, Gao Z, Liu H, Xu HE, Tang B, Cheng X, Yin W, Zhou Y, Li P
(2025) Neuron , 113 , 3567
PUBMED: 40865534
DOI: doi:10.1016/j.neuron.2025.07.029
ISSN: 0896-6273
ASTM: NERNET