EMD-65226

Single-particle
4.3 Å
EMD-65226
3D View Gallery
Deposition: 02/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65226
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9vos summary report (pdf.gz) Map and 9vos FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of GPR158 in Complex with RGS7-Gbeta5 and Nanobody Nb20

EMD-65226

Single-particle
4.3 Å
EMD-65226
3D View Gallery
Deposition: 02/07/2025
Map released: 22/07/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus, Lama glama
Sample: GPR158 complexed with Nb20
Fitted models: 9vos

Deposition Authors: Laboute T, Zucca S, Sial M, Sharma M, Brunori G, Singh S, Singh A, Martemyanov K
Targeting mGlyR with nanobodies for depression.
Laboute T, Zucca S, Sial OK, Sharma M, Brunori G, Singh S, Nageswar KV, Peng H, Rader C, Becker JA, Le Merrer J, Singh AK, Martemyanov KA
(2026) Nat Commun , 17 , 831 - 831
PUBMED: 41588006
DOI: doi:10.1038/s41467-026-68339-x
ISSN: 2041-1723