EMD-65222

Single-particle
2.7 Å
EMD-65222
3D View Gallery
Deposition: 01/07/2025
Map released: 18/03/2026
Last modified: 15/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65222
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9vo2 summary report (pdf.gz) Map and 9vo2 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the OXGR1(CA)-Gq complex

EMD-65222

Single-particle
2.7 Å
EMD-65222
3D View Gallery
Deposition: 01/07/2025
Map released: 18/03/2026
Last modified: 15/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Cryo-EM structure of the apo-OXGR1-Gq complex
Fitted models: 9vo2

Deposition Authors: Tang XJ, Sun JP, Guo LL, Li J, Deng ZL, Xiao WQ, Zhu Y, Zhu KK
Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema.
Xiao W, Zhu Y, Tang X, Zhu K, Zhang W, Chen M, Cai K, Xu S, Wu Z, Wang M, Liu J, Long L, Tan Z, Wu A, Zhou S, Zhao Z, Tang Y, Huang Y, Wang B, Liu F, Wang Q, Yang F, Jian D, Shi W, Xie H, Chen X, Guo L, Deng Z, Sun J, Li J
(2026) Cell , 189 , 1990 - 2006.e30
PUBMED: 41791372
DOI: doi:10.1016/j.cell.2026.01.036
ISSN: 1097-4172