Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-65217

Single-particle
2.51 Å
EMD-65217 Deposition: 01/07/2025
Map released: 26/11/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65217

Cryo-EM structure of a human flippase mutant ATP11C Q79E-CDC50A in PtdSer-occluded E2P-AlF state

EMD-65217

Single-particle
2.51 Å
EMD-65217 Deposition: 01/07/2025
Map released: 26/11/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ATP11C Q79E-CDC50A lipid flippase complex
Fitted models: 9vnt

Deposition Authors: Qian Y , Abe K
Cryo-EM structure of the ATP11C Q79E mutant reveals the structural basis for altered Phospholipid recognition.
Qian Y , Gopalasingam CC , Gerle C , Shigematsu H, Abe K, Oshima A
(2025) J Biol Chem , 302 , 110935 - 110935
PUBMED: 41237907
DOI: doi:10.1016/j.jbc.2025.110935
ISSN: 1083-351X
ASTM: JBCHA3
Grant Support: