EMD-65205

Single-particle
3.25 Å
EMD-65205
3D View Gallery
Deposition: 30/06/2025
Map released: 01/07/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65205

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9vna summary report (pdf.gz) Map-9vna FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of TRP melastatin channel in the desensitized state, with CHS

EMD-65205

Single-particle
3.25 Å
EMD-65205
3D View Gallery
Deposition: 30/06/2025
Map released: 01/07/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Transient receptor potential cation channel subfamily M member 8
Fitted models: 9vna

Deposition Authors: Kim S-H, Park H, Lee HH
Symmetry-driven gating of TRPM8 by PIP 2 and menthol.
Kim SH, Hong C, Park H, Ju Y, Hwang Y, Kim J, Ji S, Yu W, So I, Lee HH
(2026) Nat Commun , 17
PUBMED: 42481499
DOI: doi:10.1038/s41467-026-75793-0
ISSN: 2041-1723
Grant Support: