EMD-65194
Cryo-EM structure of the A-1-OXGR1-Gq complex
EMD-65194
Single-particle2.5 Å
Deposition: 28/06/2025Map released: 18/03/2026
Last modified: 15/04/2026
Sample Organism:
Homo sapiens,
synthetic construct
Sample: Cryo-EM structure of the apo-OXGR1-Gq complex
Fitted models: 9vmp
Deposition Authors: Tang XJ, Sun JP
,
Guo LL,
Li J,
Deng ZL,
Xiao WQ,
Zhu Y,
Zhu KK
Sample: Cryo-EM structure of the apo-OXGR1-Gq complex
Fitted models: 9vmp
Deposition Authors: Tang XJ, Sun JP
,
Guo LL,
Li J,
Deng ZL,
Xiao WQ,
Zhu Y,
Zhu KK
Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema.
Xiao W,
Zhu Y,
Tang X,
Zhu K,
Zhang W,
Chen M,
Cai K,
Xu S,
Wu Z,
Wang M,
Liu J,
Long L,
Tan Z,
Wu A,
Zhou S,
Zhao Z,
Tang Y,
Huang Y,
Wang B,
Liu F,
Wang Q,
Yang F,
Jian D,
Shi W,
Xie H,
Chen X,
Guo L,
Deng Z,
Sun J,
Li J
(2026) Cell , 189 , 1990 - 2006.e30
(2026) Cell , 189 , 1990 - 2006.e30
Grant Support: