EMD-65166

Single-particle
4.14 Å
EMD-65166 Deposition: 26/06/2025
Map released: 22/04/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65166

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9vls summary report (pdf.gz) Map-9vls FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of SARS-CoV-2 XBB.1.5 S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab (focused refinement of the S2-76E1)

EMD-65166

Single-particle
4.14 Å
EMD-65166 Deposition: 26/06/2025
Map released: 22/04/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: the local S2-76E1 map of the XBB.1.5 E-FIC-76E1 structure
Fitted models: 9vls

Deposition Authors: Liu ZM, Bao ZH, Sun XY, Sun L
Steric hindrance of antibody binding in an Omicron spike fusion intermediate.
Bao Z, Liu Z, Zhang Z, Wang X, Jin X, Bai J, Ma H, Li Y, Yi C, Ling Z, Huang Z, Zhang L, Chen Z, Xie Y, Wang Y, Sun L, Sun X
(2026) Nature , 654 , 762 - 770
PUBMED: 42092153
DOI: doi:10.1038/s41586-026-10462-2
ISSN: 1476-4687
ASTM: NATUAS