EMD-65105

Single-particle
2.62 Å
EMD-65105
3D View Gallery
Deposition: 19/06/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65105
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9vj6 summary report (pdf.gz) Map and 9vj6 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of 5-HT1AR-Gi3 in complex with F-15599

EMD-65105

Single-particle
2.62 Å
EMD-65105
3D View Gallery
Deposition: 19/06/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Cryo-EM structure of 5-HT1AR-Gi3 in complex with F-15599
Fitted models: 9vj6

Deposition Authors: Wang C, Cao C

Pathway-Selective 5-HT1AR Agonist as a Rapid Antidepressant Strategy
Wang C, Cao C
(2025) Cell