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EMD-64947
Cryo-EM structure of the human kappa opioid receptor signaling complex bound to compound A
EMD-64947
Single-particle2.76 Å
Deposition: 05/06/2025Map released: 19/11/2025
Last modified: 19/11/2025
Sample Organism:
Homo sapiens
Sample: GPCR signaling complex
Fitted models: 9v6o
Deposition Authors: Suno-Ikeda C, Sugita Y
,
Hirose M,
Suno R
Sample: GPCR signaling complex
Fitted models: 9v6o
Deposition Authors: Suno-Ikeda C, Sugita Y
,
Hirose M,
Suno R
Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor.
Suno-Ikeda C,
Nishikawa R,
Suzuki R ,
Yokoi S ,
Iwata S,
Takai T,
Ogura T,
Hirose M,
Tokuda A,
Katamoto R,
Inoue A ,
Asai E,
Kise R ,
Sugita Y ,
Kato T ,
Nagase H ,
Mitsutake A ,
Saitoh T ,
Katayama K ,
Inoue A ,
Kandori H ,
Kobayashi T ,
Suno R
(2025) Nat Commun , 16 , 9392 - 9392
,
Yokoi S ,
Iwata S,
Takai T,
Ogura T,
Hirose M,
Tokuda A,
Katamoto R,
Inoue A ,
Asai E,
Kise R ,
Sugita Y ,
Kato T ,
Nagase H ,
Mitsutake A ,
Saitoh T ,
Katayama K ,
Inoue A ,
Kandori H ,
Kobayashi T ,
Suno R
(2025) Nat Commun , 16 , 9392 - 9392
Grant Support: