EMD-64916

Single-particle
3.14 Å
EMD-64916
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Deposition: 04/06/2025
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64916
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9vb5 summary report (pdf.gz) Map and 9vb5 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the human neurotensin receptor 1 (hNTSR1)-Gi1 complex in the GDP-bound, AHD-closed C state 2, plunge-frozen 15 seconds after GDP addition

EMD-64916

Single-particle
3.14 Å
EMD-64916
3D View Gallery
Deposition: 04/06/2025
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Mus musculus
Sample: JMV449-bound human Neurotensin Receptor 1 (hNTSR1)-Gi1 complex in the GDP-bound, AHD-closed C state 2 with scFv16, plunge-frozen 15 seconds after GDP addition
Fitted models: 9vb5

Deposition Authors: Kobayashi K, Matsui TE, Fukuda M, Kawakami K, Yamashita K, Kato HE, Kato HE
The dynamic basis of G-protein recognition and activation by a GPCR.
Kobayashi K, Kawakami K, Matsui TE, Yokoi S, Fukuda M, Narita TJ, Arai H, Tambo M, Sumikama T, Tatsumi M, Yamashita K, Koyanagi J, Kugawa M, Ikeda H, Sumino A, Mitsutake A, Kobilka BK, Inoue A, Kato HE
(2026) Nature , 652 , 812 - 821
PUBMED: 41813902
DOI: doi:10.1038/s41586-026-10228-w
ISSN: 1476-4687
ASTM: NATUAS