EMD-64869

Helical reconstruction
2.62 Å
EMD-64869
3D View Gallery
Deposition: 30/05/2025
Map released: 08/04/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64869
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9v9c summary report (pdf.gz) Map and 9v9c FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human TNFR1 DD filament

EMD-64869

Helical reconstruction
2.62 Å
EMD-64869
3D View Gallery
Deposition: 30/05/2025
Map released: 08/04/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TNFR1 DD filament
Fitted models: 9v9c

Deposition Authors: Zhao K , Liu JP, Liu C , Yuan JY
Electric dipole moment drives the dynamics of the TNFR1 complex I signalosome.
Liu J , Zhao J , Gao J, Zhao K , Han Y , Yang J , Li Z , Ye J , Sun Z , Wang F, Liu X, Li Z , Ji S, Liu B, Liu C , Zhang Y , Yuan J , Chou JJ
(2026) Nature , 653 , 1196 - 1204
PUBMED: 41922760
DOI: doi:10.1038/s41586-026-10304-1
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: