EMD-64830

Single-particle
2.56 Å
EMD-64830
3D View Gallery
Deposition: 29/05/2025
Map released: 06/05/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64830

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9v82 summary report (pdf.gz) Map-9v82 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Local refine map of HEP-50768-bound MRGPRX4

EMD-64830

Single-particle
2.56 Å
EMD-64830
3D View Gallery
Deposition: 29/05/2025
Map released: 06/05/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Structure of an antagonist-bound MRGPRX4-Gq complex
Fitted models: 9v82

Deposition Authors: Wang C, Zhang M, Cao C
Development of a clinically viable MRGPRX4 inverse agonist for cholestatic itch treatment.
Yang J , Shen R, Wang C, Zhu W, Ke H, Fan J , Zhang M, Liu Y, Li S, Li G, Wang X, Li Y , Cao C , Lei X
(2026) Nat Chem Biol
PUBMED: 41957282
DOI: doi:10.1038/s41589-026-02195-0
ISSN: 1552-4469