EMD-64830

Single-particle
2.56 Å
EMD-64830
3D View Gallery
Deposition: 29/05/2025
Map released: 06/05/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64830

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9v82 summary report (pdf.gz) Map-9v82 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Local refine map of HEP-50768-bound MRGPRX4

EMD-64830

Single-particle
2.56 Å
EMD-64830
3D View Gallery
Deposition: 29/05/2025
Map released: 06/05/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Structure of an antagonist-bound MRGPRX4-Gq complex
Fitted models: 9v82

Deposition Authors: Wang C, Zhang M, Cao C
Development of a clinically viable MRGPRX4 inverse agonist for cholestatic itch treatment.
Yang J, Shen R, Wang C, Zhu W, Ke H, Fan J, Zhang M, Liu Y, Li S, Li G, Wang X, Li Y, Cao C, Lei X
(2026) Nat Chem Biol
PUBMED: 41957282
DOI: doi:10.1038/s41589-026-02195-0
ISSN: 1552-4469