EMD-64606

Single-particle
2.52 Å
EMD-64606
3D View Gallery
Deposition: 14/05/2025
Map released: 02/07/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64606

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9uy3 summary report (pdf.gz) Map-9uy3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Anamorelin bound growth hormone secretagogue receptor in complex with Gq

EMD-64606

Single-particle
2.52 Å
EMD-64606
3D View Gallery
Deposition: 14/05/2025
Map released: 02/07/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: GQ bound GHSR in complex with Anamorelin
Fitted models: 9uy3

Deposition Authors: Wang R, Sun J, Liu H, Guo S, Zhang Y, Hu W, Wang J, Liu H, Zhuang Y, Jiang Y, Xie X, Xu HE, Wang Y
Molecular recognition of two approved drugs Macimorelin and Anamorelin by the growth hormone secretagogue receptor.
Wang RL, Sun J, Liu H, Guo SM, Zhang Y, Hu W, Wang J, Liu H, Zhuang YW, Jiang Y, Xie X, Xu HE, Wang Y
(2025) Acta Pharmacol.Sin. , 46 , 2998 - 3008
PUBMED: 40542284
DOI: doi:10.1038/s41401-025-01606-7
ISSN: 1745-7254