EMD-64539

Single-particle
2.89 Å
EMD-64539
3D View Gallery
Deposition: 11/05/2025
Map released: 06/05/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64539

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9uvw summary report (pdf.gz) Map-9uvw FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of Vasopressin receptor 2 (V2R)-BRIL/anti BRIL SRP2070 Fab antibody complex with tolvaptan, focused on receptor

EMD-64539

Single-particle
2.89 Å
EMD-64539
3D View Gallery
Deposition: 11/05/2025
Map released: 06/05/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of Vasopressin receptor 2 (V2R)-BRIL/anti BRIL SRP2070 Fab antibody complex with tolvaptan, focused on receptor
Fitted models: 9uvw

Deposition Authors: Kojima A, Kawakami K, Kobayashi K, Matsui TE, Fukuda M, Kato HE
A Rapid and Universal Pipeline for High-Resolution GPCR Structure Determination through <em>In Silico</em> Construct Optimization and de novo Protein Design
Kojima A, Kawakami K, Kobayashi N, Kobayashi K, Matsui TE, Uemoto K, Gu Y, Fukuda M, Kato HE
(2026) bioRxiv
DOI: doi:10.64898/2026.04.02.716066
ISSN: 2692-8205