EMD-64369

Single-particle
2.9 Å
EMD-64369 Deposition: 24/04/2025
Map released: 10/12/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64369

Cryo-EM structure of human organic solute transporter Ost-alpha/beta bound with DHEAS

EMD-64369

Single-particle
2.9 Å
EMD-64369 Deposition: 24/04/2025
Map released: 10/12/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Heterodimer of Ost alpha and Ost beta
Fitted models: 9uo1

Deposition Authors: Yang X , Xu E
Structures of Ost alpha / beta reveal a unique fold and bile acid transport mechanism.
Yang X , Cui N, Li T, He X , Zhang H, Wu C, Li Y , Ma X , Xu HE
(2026) Nature , 651 , 260 - 267
PUBMED: 41606328
DOI: doi:10.1038/s41586-025-10029-7
ISSN: 1476-4687
ASTM: NATUAS