EMD-64038
structure of human KCNQ1-KCNE1-CaM complex with PIP2
EMD-64038
Single-particle3.36 Å
Deposition: 03/04/2025Map released: 05/11/2025
Last modified: 19/11/2025
Sample Organism:
Homo sapiens
Sample: Structure of human KCNQ1-KCNE1-CaM complex
Fitted models: 9uc8
Deposition Authors: Hou PP, Zhang J
,
Wan SY,
Cheng XY,
Zhong L ,
Hu B
Sample: Structure of human KCNQ1-KCNE1-CaM complex
Fitted models: 9uc8
Deposition Authors: Hou PP, Zhang J
,
Wan SY,
Cheng XY,
Zhong L ,
Hu B
Secondary structure transitions and dual PIP2 binding define cardiac KCNQ1-KCNE1 channel gating.
Zhong L ,
Lin X ,
Cheng X ,
Wan S,
Hua Y,
Nan W,
Hu B ,
Peng X ,
Zhou Z,
Zhang Q ,
Yang H ,
Noe F,
Yan Z,
Jiang D,
Zhang H,
Liu F,
Xiao C,
Zhou Z,
Mou Y,
Yu H ,
Ma L,
Huang C,
Wong VKW,
Chung SK,
Shen B,
Jiang ZH ,
Neher E,
Zhu W ,
Zhang J ,
Hou P
(2025) Cell Res , 35 , 887 - 899
,
Lin X ,
Cheng X ,
Wan S,
Hua Y,
Nan W,
Hu B ,
Peng X ,
Zhou Z,
Zhang Q ,
Yang H ,
Noe F,
Yan Z,
Jiang D,
Zhang H,
Liu F,
Xiao C,
Zhou Z,
Mou Y,
Yu H ,
Ma L,
Huang C,
Wong VKW,
Chung SK,
Shen B,
Jiang ZH ,
Neher E,
Zhu W ,
Zhang J ,
Hou P
(2025) Cell Res , 35 , 887 - 899
Grant Support: