EMD-63988

Single-particle
3.62 Å
EMD-63988
3D View Gallery
Deposition: 01/04/2025
Map released: 29/10/2025
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-63988

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9uap summary report (pdf.gz) Map-9uap FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

cryo-EM structure of ligand-free active-state M1 muscarinic acetylcholine receptor with alpha5 helix of G11 protein complex

EMD-63988

Single-particle
3.62 Å
EMD-63988
3D View Gallery
Deposition: 01/04/2025
Map released: 29/10/2025
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ligand-free active-state M1 muscarinic acetylcholine receptor with alpha5 helix of G11 protein complex/de novo design fusion protein
Fitted models: 9uap

Deposition Authors: Zhang X , Gao K , Liu X
Extracellular nanobody screening using conformationally stable GPCR variants.
Zhang X , Gao K , Nie J, Meng H, Sun X, Zhao J, Liu X
(2025) PNAS , 122 , e2508879122 - e2508879122
PUBMED: 41187083
DOI: doi:10.1073/pnas.2508879122
ISSN: 1091-6490
ASTM: PNASA6