EMD-63505

Single-particle
3.67 Å
EMD-63505
3D View Gallery
Deposition: 19/02/2025
Map released: 04/03/2026
Last modified: 15/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-63505

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ly6 summary report (pdf.gz) Map-9ly6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

antibody 20G5 (Fab')2 in complex with human B7-H3

EMD-63505

Single-particle
3.67 Å
EMD-63505
3D View Gallery
Deposition: 19/02/2025
Map released: 04/03/2026
Last modified: 15/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: antibody 20G5 (Fab')2 in complex with human B7-H3
Fitted models: 9ly6

Deposition Authors: Li B, Zhou S, He K
B7-H3-mediated cis-inhibition of EGFR by a tumor-selective bispecific antibody enhances anti-tumor efficacy and minimizes toxicities.
Guan J, Chia T, Li B, Zhu T, Liao Z, Deng J, Fu F, Wu W , Liu C, Liu Y, Li N, Yue L, Cao L, Lu J, Zhu M, Ling X, Zheng H, Lin S, Li L, Zhou S, He K
(2026) Nat Commun , 17
PUBMED: 41735305
DOI: doi:10.1038/s41467-026-69703-7
ISSN: 2041-1723
Grant Support: