EMD-63488

Single-particle
3.2 Å
EMD-63488
3D View Gallery
Deposition: 19/02/2025
Map released: 04/03/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-63488

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9lxp summary report (pdf.gz) Map-9lxp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

A Cryo-EM structure of LA-PTH-PTH1R-Beta-arrestin1 complex (state 2 conformation)

EMD-63488

Single-particle
3.2 Å
EMD-63488
3D View Gallery
Deposition: 19/02/2025
Map released: 04/03/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: A Cryo-EM structure of LA-PTH-PTH1R-Beta-arrestin1 complex (state 2 conformation)
Fitted models: 9lxp

Deposition Authors: Zhao L , Yuan Q
Structural basis of PTH1R-beta-arrestin core engagement reveals design principles for G-protein-biased therapeutics.
Zhao LH, He Q, Yuan Q, Zhang M, Zhao GG, Sun J, Hu W, Shan H, Xu HE
(2026) Nat Struct Mol Biol , 33 , 868 - 881
PUBMED: 42115346
DOI: doi:10.1038/s41594-026-01806-7
ISSN: 1545-9985