EMD-63441

Single-particle
3.46 Å
EMD-63441
3D View Gallery
Deposition: 14/02/2025
Map released: 18/02/2026
Last modified: 02/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-63441

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

A focused Cryo_EM structure of LA_PTH_PTH1R_Beta_arrestin1 complex(state 1 conformation)

EMD-63441

Single-particle
3.46 Å
EMD-63441
3D View Gallery
Deposition: 14/02/2025
Map released: 18/02/2026
Last modified: 02/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: A Cryo-EM structure of LA-PTH-PTH1R-B-arrestin1 complex (state 1 conformation)

Deposition Authors: Yuan Q, Yuan Q
Structural basis of PTH1R-beta-arrestin core engagement reveals design principles for G-protein-biased therapeutics.
Zhao LH, He Q, Yuan Q, Zhang M, Zhao GG, Sun J, Hu W, Shan H, Xu HE
(2026) Nat Struct Mol Biol , 33 , 868 - 881
PUBMED: 42115346
DOI: doi:10.1038/s41594-026-01806-7
ISSN: 1545-9985