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EMD-63091
human alpha 7 nicotinic acetylcholine receptor in complex with L-nicotine (meta-three-nicotine-bound desensitized state)
EMD-63091
Single-particle2.96 Å
Deposition: 11/01/2025Map released: 10/09/2025
Last modified: 29/10/2025
Sample Organism:
Homo sapiens
Sample: human alpha 7 nicotinic acetylcholine receptor in complex with L-nicotine
Fitted models: 9lha
Deposition Authors: Liu S
,
Chen H ,
Tian C
Sample: human alpha 7 nicotinic acetylcholine receptor in complex with L-nicotine
Fitted models: 9lha
Deposition Authors: Liu S
,
Chen H ,
Tian C
Structural insights into the progressive recovery of alpha 7 nicotinic acetylcholine receptor from nicotine-induced desensitization.
Liu S ,
Chen H ,
Zhu X ,
Ye F,
Zhao Y,
Qin J ,
Zheng Y,
Wang X,
Zhang L,
Chen H ,
Li X ,
Mu W,
Fu Y,
Luo C ,
Hou H ,
Bai C ,
Liu L ,
Tian C
(2025) Sci Adv , 11 , eadx4432 - eadx4432
,
Chen H ,
Zhu X ,
Ye F,
Zhao Y,
Qin J ,
Zheng Y,
Wang X,
Zhang L,
Chen H ,
Li X ,
Mu W,
Fu Y,
Luo C ,
Hou H ,
Bai C ,
Liu L ,
Tian C
(2025) Sci Adv , 11 , eadx4432 - eadx4432
Grant Support: