EMD-62598

Single-particle
2.79 Å
EMD-62598
3D View Gallery
Deposition: 05/12/2024
Map released: 26/11/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62598

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9kvp summary report (pdf.gz) Map-9kvp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of SB290157 bound to human C3aR in complex with Go (Full map)

EMD-62598

Single-particle
2.79 Å
EMD-62598
3D View Gallery
Deposition: 05/12/2024
Map released: 26/11/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: SB290157 bound to human C3aR in complex with Go
Fitted models: 9kvp

Deposition Authors: Banerjee R, Sano FK, Yadav MK, Sawada K, Ganguly M, Mishra S, Dalal A, Nureki O, Shukla AK
Molecular fingerprints of a convergent mechanism orchestrating diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptors.
Mishra S, Yadav MK, Dalal A, Ganguly M, Yadav R, Sawada K, Tiwari D, Roy N, Banerjee N, Fung JN, Marallag J, Cui CS, Li XX, Lee JD , Dsouza CA, Saha S, Sarma P, Rawat G, Zhu H, Khant HA, Clark RJ, Sano FK, Banerjee R, Woodruff TM , Nureki O, Gati C, Shukla AK
(2025) bioRxiv
PUBMED: 40501890
DOI: doi:10.1101/2025.05.26.656101
ISSN: 2692-8205