Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-62498

Single-particle
3.28 Å
EMD-62498
3D View Gallery
Deposition: 25/11/2024
Map released: 15/01/2025
Last modified: 15/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62498
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9kqa summary report (pdf.gz) Map and 9kqa FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human VMAT2 in complex with Tetrabenazine

EMD-62498

Single-particle
3.28 Å
EMD-62498
3D View Gallery
Deposition: 25/11/2024
Map released: 15/01/2025
Last modified: 15/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: VMAT2
Fitted models: 9kqa

Deposition Authors: Wei F , Zhang W, Zhang Y
Drug inhibition and substrate transport mechanisms of human VMAT2.
Wei F , Liu H , Zhang W, Wang J, Zhang Y
(2025) Nat Commun , 16 , 323 - 323
PUBMED: 39747030
DOI: doi:10.1038/s41467-024-55361-0
ISSN: 2041-1723