EMD-62323
Cryo-EM structure of simian rotavirus SA11 TLP in complex with nAb 41# (37 degree Celsius, 1 h)
EMD-62323
Single-particle3.96 Å
Deposition: 09/11/2024Map released: 22/01/2025
Last modified: 13/08/2025
Sample Organism:
Rotavirus A,
Homo sapiens
Sample: Immune complex of rotavirus SA11 TLP with antibody 41# following a 1-hour incubation at 37 degree Celsius
Deposition Authors: Huang Y, Sun H
,
Song F ,
Zheng Q ,
Li S ,
Xia N
Sample: Immune complex of rotavirus SA11 TLP with antibody 41# following a 1-hour incubation at 37 degree Celsius
Deposition Authors: Huang Y, Sun H
,
Song F ,
Zheng Q ,
Li S ,
Xia N
A single residue switch mediates the broad neutralization of Rotaviruses.
Huang Y,
Song F ,
Zeng Y,
Sun H ,
Sheng R,
Wang X,
Liu L,
Luo G,
Jiang Y,
Chen Y,
Zhang M,
Zhang S ,
Gu Y ,
Yu H ,
Li S ,
Li T ,
Zheng Q ,
Ge S ,
Zhang J ,
Xia N
(2025) Nat Commun , 16 , 838 - 838
,
Zeng Y,
Sun H ,
Sheng R,
Wang X,
Liu L,
Luo G,
Jiang Y,
Chen Y,
Zhang M,
Zhang S ,
Gu Y ,
Yu H ,
Li S ,
Li T ,
Zheng Q ,
Ge S ,
Zhang J ,
Xia N
(2025) Nat Commun , 16 , 838 - 838
Grant Support: