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EMD-62299

Single-particle
2.95 Å
EMD-62299 Deposition: 06/11/2024
Map released: 13/08/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62299

Cryo-EM structure of the relaxin-3-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex

EMD-62299

Single-particle
2.95 Å
EMD-62299 Deposition: 06/11/2024
Map released: 13/08/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Bos taurus
Sample: Cryo-EM structure of the human relaxin family peptide receptor 4 in complex with relaxin-3 and G protein
Fitted models: 9kfk

Deposition Authors: Chen Y, Zhou QT, Yan SY, Yan JH, Yang DH, Chen J, Wang MW , Zhu Q, Zhao FH, Li CH, Chen CW, Cai XQ, Bathgate RAD, Shen C, Liu H, Xu HE, Yang DH, Wang MW
Molecular mechanism underlying non-discriminatory recognition of relaxin-3 by RXFP3 and RXFP4.
Chen Y, Zhou Q, Yan S, Yan J , Yang D , Chen J, Wang MW
(2025) Commun Biol , 8 , 794 - 794
PUBMED: 40410443
DOI: doi:10.1038/s42003-025-08220-7
ISSN: 2399-3642