EMD-62282

Single-particle
2.96 Å
EMD-62282
3D View Gallery
Deposition: 03/11/2024
Map released: 12/11/2025
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62282

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9kdn summary report (pdf.gz) Map-9kdn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The structure of 1 ACTD bound to RNA polymerase II elongation complex with 2 CTG repeats.

EMD-62282

Single-particle
2.96 Å
EMD-62282
3D View Gallery
Deposition: 03/11/2024
Map released: 12/11/2025
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae S288C, synthetic construct, Streptomyces sp.
Sample: The structure of 1 ACTD bound to RNA polymerase II elongation complex with 2 CTG repeats
Fitted models: 9kdn

Deposition Authors: Xu J, Zhao W, Zhu L
Stepwise transcription stalling by the anti-cancer drug Actinomycin D and insights into short tandem repeat transcription inhibition.
Zhao W, Zhu L, Liu Y, Deng W, Yang X, Ye L, Lin Z, Ding K, Yang X, Li X, Xu J
(2026) Nat Commun , 17
PUBMED: 41833943
DOI: doi:10.1038/s41467-026-70612-y
ISSN: 2041-1723