EMD-62264

Single-particle
3.09 Å
EMD-62264
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Deposition: 03/11/2024
Map released: 12/11/2025
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62264
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9kd7 summary report (pdf.gz) Map and 9kd7 FULL report (pdf.gz)
EMICSS annotations (xml)

The structure of RNA polymerase II elongation complex paused at N-1 state by actinomycin D.

EMD-62264

Single-particle
3.09 Å
EMD-62264
3D View Gallery
Deposition: 03/11/2024
Map released: 12/11/2025
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae S288C, synthetic construct, Saccharomyces cerevisiae, Streptomyces sp.
Sample: DNA-directed RNA polymerase II elongation complex in complex with actinomycin D at n-1 state
Fitted models: 9kd7

Deposition Authors: Xu J , Zhao W , Zhu L
Stepwise transcription stalling by the anti-cancer drug Actinomycin D and insights into short tandem repeat transcription inhibition.
Zhao W , Zhu L , Liu Y, Deng W, Yang X, Ye L, Lin Z, Ding K, Yang X, Li X, Xu J
(2026) Nat Commun , 17
PUBMED: 41833943
DOI: doi:10.1038/s41467-026-70612-y
ISSN: 2041-1723