EMD-62184

Single-particle
3.86 Å
EMD-62184
3D View Gallery
Deposition: 25/10/2024
Map released: 15/07/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62184
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9k91 summary report (pdf.gz) Map and 9k91 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human histone deacetylase 6 tandem catalytic domain (HDAC6 CD1-2)

EMD-62184

Single-particle
3.86 Å
EMD-62184
3D View Gallery
Deposition: 25/10/2024
Map released: 15/07/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human HDAC6 catalytic domain (CD1-2)
Fitted models: 9k91

Deposition Authors: Sun C, Xie K, Zhu Z, Chao Y, Zhou Z, Qu Q, Zhu Y

Hydrogen sulfide binds to the zinc-active-site of hHDAC6 to increase enzyme activity via an H2S-mediated deacetylation pathway
Sun C, Wang Y, Cai S, Xie K, Li M, Zhu Z, Chao Y, Zhou Z, Chen Y, Xue W, Mu X, Bian X, Miao W, Wu J, Ding Q, Wang M, Tao B, Zhang I, Zhu Y, Qu Q, Zhu Y
To Be Published