EMD-61982

Single-particle
3.5 Å
EMD-61982
3D View Gallery
Deposition: 16/10/2024
Map released: 03/09/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61982

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9k1w summary report (pdf.gz) Map-9k1w FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the SF3B core, harboring the K700E mutation in SF3B1, in complex with intron-U2 snRNA

EMD-61982

Single-particle
3.5 Å
EMD-61982
3D View Gallery
Deposition: 16/10/2024
Map released: 03/09/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: SF3B core with K700E mutation in SF3B1 complexed with intron-U2 snRNA
Fitted models: 9k1w

Deposition Authors: Zhang Y, Yin C, Huang J
A common structural mechanism for RNA recognition by the SF3B complex in mRNA splicing and export.
Zhang Y, Yin C, Wang Y, Yan K, Zhao B, Hu X, Wan Y , Cheng H , Huang J
(2025) Nucleic Acids Res , 53
PUBMED: 40795960
DOI: doi:10.1093/nar/gkaf759
ISSN: 1362-4962
ASTM: NARHAD
Grant Support: