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EMD-61867
Cryo-EM structure of human XPR1 in an open state at the intracellular gate and a closed state at the extracellular gate, obtained through local refinement
EMD-61867
Single-particle3.23 Å
Deposition: 11/10/2024Map released: 27/08/2025
Last modified: 17/09/2025
Sample Organism:
Homo sapiens
Sample: Homodimer of XPR1
Fitted models: 9jxl
Deposition Authors: Wang X, Bai Z, Wallis C, Wang H, Han Y, Jin R, Lei M
,
Gu C,
Jessen H ,
Shears S,
Sun Y,
Corry B ,
Zhang Y
Sample: Homodimer of XPR1
Fitted models: 9jxl
Deposition Authors: Wang X, Bai Z, Wallis C, Wang H, Han Y, Jin R, Lei M
,
Gu C,
Jessen H ,
Shears S,
Sun Y,
Corry B ,
Zhang Y
KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1.
Wang X,
Bai Z,
Wallis C,
Wang H,
Han Y,
Jin R,
Lei M ,
Yang T,
Gu C,
Jessen H ,
Shears S,
Sun Y,
Corry B ,
Zhang Y
(2025) Mol Cell , 85 , 3209 - 3224.e8
,
Yang T,
Gu C,
Jessen H ,
Shears S,
Sun Y,
Corry B ,
Zhang Y
(2025) Mol Cell , 85 , 3209 - 3224.e8
Grant Support: