Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-61847

Single-particle
2.56 Å
EMD-61847
3D View Gallery
Deposition: 09/10/2024
Map released: 19/03/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61847
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9jvz summary report (pdf.gz) Map and 9jvz FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of M. tuberculosis ClpP1P2 bound to bortezomib

EMD-61847

Single-particle
2.56 Å
EMD-61847
3D View Gallery
Deposition: 09/10/2024
Map released: 19/03/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis H37Rv, Mycobacterium tuberculosis
Sample: CryoEM structure of M. tuberculosis BTZ-ClpP1P2 complex
Fitted models: 9jvz

Deposition Authors: Zhou B, Zhao H, Gao Y, Chen W, Zhang T, He J, Xiong X

Activation mechanism of caseinolytic chaperone-protease system in Mycobacterium tuberculosis by the anti-cancer drug bortezomib
Zhou B, Zhao H, Gao Y, Chen X, Zhang T, He J, Xiong X
To Be Published