EMD-61798
Cryo-EM structure of PTH-PTH1R-Gq complex (tilted state; focused refinement map)
EMD-61798
Single-particle2.75 Å
Deposition: 04/10/2024Map released: 16/10/2024
Last modified: 10/12/2025
Sample Organism:
Homo sapiens
Sample: PTH-PTH1R-Gq complex
Deposition Authors: Sano FK
,
Hirano H,
Itoh Y ,
Nureki O
Sample: PTH-PTH1R-Gq complex
Deposition Authors: Sano FK
,
Hirano H,
Itoh Y ,
Nureki O
Insights into G-protein coupling preference from cryo-EM structures of G q -bound PTH1R.
Sano FK ,
Shimizume K,
Kobayashi K ,
Awazu T ,
Kawakami K ,
Akasaka H ,
Kobayashi TA ,
Tanaka T ,
Okamoto HH,
Hirano H,
Kusakizako T ,
Shihoya W ,
Kise Y,
Itoh Y ,
Ishitani R,
Okada Y ,
Sako Y ,
Yanagawa M ,
Inoue A ,
Nureki O
(2025) Nat Chem Biol , 21 , 1906 - 1914
,
Shimizume K,
Kobayashi K ,
Awazu T ,
Kawakami K ,
Akasaka H ,
Kobayashi TA ,
Tanaka T ,
Okamoto HH,
Hirano H,
Kusakizako T ,
Shihoya W ,
Kise Y,
Itoh Y ,
Ishitani R,
Okada Y ,
Sako Y ,
Yanagawa M ,
Inoue A ,
Nureki O
(2025) Nat Chem Biol , 21 , 1906 - 1914
Grant Support: