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EMD-61741

Single-particle
2.7 Å
EMD-61741
3D View Gallery
Deposition: 28/09/2024
Map released: 18/12/2024
Last modified: 18/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61741
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9jqt summary report (pdf.gz) Map and 9jqt FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of interleukin receptor common gamma chain (IL2Rgamma/CD132) in complex with 2D4

EMD-61741

Single-particle
2.7 Å
EMD-61741
3D View Gallery
Deposition: 28/09/2024
Map released: 18/12/2024
Last modified: 18/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Interleukin receptor common gamma chain (IL2Rgamma/CD132) in complex with 2D4
Fitted models: 9jqt

Deposition Authors: Lu QJ, Yin HQ
2D4, a humanized monoclonal antibody targeting CD132, is a promising treatment for systemic lupus erythematosus.
Yin H, Li L, Feng X, Wang Z, Zheng M, Zhao J, Fan X, Wu W, Gao L, Zhan Y, Zhao M, Lu Q
(2024) Signal Transduct Target Ther , 9 , 323 - 323
PUBMED: 39551768
DOI: doi:10.1038/s41392-024-02017-6
ISSN: 2059-3635