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EMD-61643

Single-particle
3.4 Å
EMD-61643
3D View Gallery
Deposition: 24/09/2024
Map released: 26/02/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61643
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9jo4 summary report (pdf.gz) Map and 9jo4 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human BKca channel-compound 51b complex

EMD-61643

Single-particle
3.4 Å
EMD-61643
3D View Gallery
Deposition: 24/09/2024
Map released: 26/02/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: BKca channel-compound 51b complex
Fitted models: 9jo4

Deposition Authors: Kim S, Park S, Lee NY, Lee EY, Lee N, Roh EC, Kim YG, Kim HJ , Jin MS, Park CS , Kim YC
Discovery of Diphenyl Ether Derivatives as Novel BK Ca Channel Activators: Structure-Activity Relationship, Cryo-EM Complex Structures, and In Vivo Animal Studies.
Park SB , Lee NY, Lee EY, Kim S, Lee N, Roh EC, Kim YG, Kim HJ , Jin MS, Park CS , Kim YC
(2025) J Med Chem , 68 , 4259 - 4286
PUBMED: 39947888
DOI: doi:10.1021/acs.jmedchem.4c02008
ISSN: 0022-2623
ASTM: JMCMAR
Grant Support: