Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-61603

Single-particle
3.3 Å
EMD-61603 Deposition: 20/09/2024
Map released: 18/06/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61603

Cryo-EM structure of CN-HedgehogCoV (HKU31/Erinaceus amurensis/China/2014) S-trimer in a locked-2 conformation

EMD-61603

Single-particle
3.3 Å
EMD-61603 Deposition: 20/09/2024
Map released: 18/06/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Erinaceus hedgehog coronavirus HKU31, Enterobacteria phage T4
Sample: CN-HedgehogCoV (HKU31/Erinaceus amurensis/China/2014) Spike protein
Fitted models: 9jmi

Deposition Authors: Yuan H , Xiong X
Structures and receptor binding activities of merbecovirus spike proteins reveal key signatures for human DPP4 adaptation.
Yuan H , Wang J , Ma Y , Li Z , Gao X , Habib G , Liu B, Chen J, He J, Zhou P , Shi ZL , Chen X , Xiong X
(2025) Sci Adv , 11 , eadv7296 - eadv7296
PUBMED: 40644548
DOI: doi:10.1126/sciadv.adv7296
ISSN: 2375-2548